Your doctor will show you how to self-inject Byetta when you first start the treatment. You can also ask your pharmacist to show you the best way to give yourself your Byetta doses. For details about how to self-inject Byetta, see these step-by-step instructions. The information below describes commonly used dosages. Your dosing frequency how often you use Byetta will depend on how you respond to the drug. Your doctor will decide on the right dosage for you.
Byetta comes in two strengths: 5 micrograms mcg of Byetta per dose in 1. Typically, your doctor will start you on a low dosage of Byetta. Your doctor will ultimately prescribe the smallest dosage that has the desired effect. The information below describes dosages that are commonly used or recommended. But be sure to use the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. The typical starting dosage of Byetta is 5 mcg injected twice per day.
After this, depending on how you respond to Byetta, your doctor may increase your dosage to 10 mcg injected twice per day. You should inject your Byetta doses 1 hour before each of your two main meals for example, breakfast and dinner. The two doses should be at least 6 hours apart. Once you decide when to have your two daily doses, try to stick with this schedule. This will help keep your blood sugar levels steady throughout the day. Yes, Byetta is typically used as a long-term treatment.
You may need dosage adjustments, depending on:. If you have questions about whether Byetta is safe for you because of your health conditions or other factors, talk with your doctor. Below are answers to some asked questions about Byetta.
If you have other questions about the drug, talk with your doctor or pharmacist. No, Byetta is not approved for use as a weight loss drug. But because Byetta is used along with a healthy diet and exercise program, you may lose weight while using the drug. Also, studies show Byetta can cause loss of appetite. This, too, may lead to weight loss. Losing weight and using Byetta along with making diet and exercise changes can reduce your blood sugar levels. It can be dangerous if your levels drop too low.
If you have questions or concerns about losing weight during your Byetta treatment, talk with your doctor. It only comes as self-injection pens that are used twice per day. To learn more about how these drugs are similar and different, see this comparison. If you have questions about which diabetes treatment is right for you, talk with your doctor.
Byetta is a liquid solution that comes in prefilled disposable pens. You can also follow these step-by-step instructions. You can also ask your pharmacist to show you how to use the injection pen if you still have questions.
Instead, just skip the missed dose and inject your next dose at its regular time. Be sure to check your blood sugar levels regularly so you can maintain steady levels. This can drop your blood sugar level dangerously low and cause serious side effects.
If you need help remembering to inject Byetta on time, try using a medication reminder. This can include setting an alarm, downloading a reminder app, or setting a timer on your phone. A kitchen timer can work, too. Using more than this can lead to serious side effects, such as hypoglycemia low blood sugar. You can also call to reach the American Association of Poison Control Centers, or use their online resource.
But if you have severe symptoms, call or your local emergency number immediately or go to the nearest emergency room. However, it has been reported by some people using Byetta since the drug was approved. A literature review of safety issues with Byetta and other drugs in the same class did not find any association between pancreatic cancer and use of these drugs.
However, the long-acting form of exenatide, which is the main drug in Byetta, does have such a warning. This form of exenatide is available as the brand-name drug Bydureon. An FDA boxed warning is used to alert doctors and patients about potentially serious side effects that might be associated with a drug. Bydureon has one because it was shown to cause thyroid cancer in some animals. However, results from animal studies do not necessarily apply to humans. The FDA has also issued boxed warnings about thyroid cancer for other medications in the same drug class as Byetta.
These drugs are liraglutide Victoza , semaglutide Ozempic , albiglutide Tanzeum , and dulaglutide Trulicity. These warnings are also based on animal studies. However, these drugs have not been shown to cause thyroid cancer in humans. This is because data needs to be collected over a very long period of time. As with all medications, the cost of Byetta can vary. To find current prices for Byetta in your area, check out GoodRx. The cost you find on GoodRx. If you need financial support to pay for Byetta, or if you need help understanding your insurance coverage, help is available.
AstraZeneca, the manufacturer of Byetta, offers a savings card called MySavingsRx, which can help lower the cost of Byetta. To learn more, call or visit the program website. Other drugs are available for treating type 2 diabetes. Some may be a better fit for you than others.
They can tell you about other medications that may work well for you. You may wonder how Byetta compares to other medications that are prescribed for similar uses.
Here we look at how Byetta and Bydureon are alike and different. Byetta and Bydureon are both FDA-approved to help control blood sugar levels in adults with type 2 diabetes. They are used along with a diet and exercise program. Both of these medications contain exenatide, so they work the same way in the body.
Byetta is a short-acting form of the drug that wears off after a few hours. Bydureon is a long-acting form of exenatide that works for a longer period. Byetta comes as a prefilled multidose injection pen.
You give yourself an injection under your skin subcutaneous twice a day, before your main meals. Bydureon comes as a single-dose injection pen or a single-dose syringe.
It also comes as a single-dose prefilled autoinjector called Bydureon BCise. With all forms of Bydureon, you give yourself an injection under your skin once a week, on the same day each week.
Byetta and Bydureon both contain exenatide. Therefore, both medications can cause very similar side effects. Below are examples of these side effects. These lists contain examples of more common side effects that can occur with Byetta, with Bydureon, or with both drugs when taken individually.
These lists contain examples of serious side effects that occur with Bydureon, and both Bydureon and Byetta when taken individually. A boxed warning is the strongest warning the FDA requires. It alerts doctors and patients about drug effects that may be dangerous. Byetta and Bydureon have been directly compared in a clinical study. In this study, the effectiveness of the drugs was compared when they were both used on their own and when they were used in combination with other diabetes drugs.
The study found that on average, Bydureon lowered hemoglobin by 0. Over the same time period, people treated with Bydureon had an average weight loss of 5 lb. People treated with Byetta lost an average of 3 lb.
Byetta and Bydureon are both brand-name drugs. There are currently no generic forms of either drug. Brand-name medications usually cost more than generics. According to estimates on GoodRx. Byetta and Victoza are prescribed for similar uses. Below are details of how these medications are alike and different. Byetta and Victoza are both FDA-approved to help control blood sugar levels in adults with type 2 diabetes.
They are both used along with a diet and exercise program. Victoza is also FDA-approved to reduce the risk of heart attacks and strokes in people with type 2 diabetes who have heart disease. Byetta contains exenatide, and Victoza contains liraglutide. These medications are from the same drug class, so they work in the same way in the body. With Byetta, you give yourself an injection under your skin subcutaneous twice a day, before your main meals. With Victoza, you give yourself an injection under your skin once a day, at any time of day.
Byetta and Victoza contain drugs from the same class. These lists contain examples of more common side effects that can occur with Byetta, with Victoza, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Victoza, and with both Byetta and Victoza when taken individually. Byetta and Victoza have been directly compared in a clinical study.
In this study, the effectiveness of the drugs was compared when they were both used in combination with other drugs to treat diabetes metformin , a sulfonylurea, or both.
The study found that, on average, Victoza lowered hemoglobin A1c HbA1c by 0. Over the same period, people treated with Victoza and people treated with Byetta both lost an average of 6. Byetta and Victoza are both brand-name drugs. Byetta may also be used off-label for other conditions. Byetta is FDA-approved to help control blood sugar levels in adults with type 2 diabetes. This leads to high blood sugar levels. Byetta reduces hemoglobin A1c HbA1c , which is a measure of your average blood sugar levels over 3 months.
Byetta helps lower your blood sugar after eating a meal. It also lowers your blood sugar between meals.
This is called your fasting blood sugar level. Byetta can also help some people lose weight. Byetta may be used on its own or with other diabetes medications. These other medications include metformin , glipizide, and pioglitazone. In a clinical study of people using Byetta on its own:.
When used with another diabetes drug, Byetta is most often used with metformin. In a clinical study of people treated with Byetta and metformin:. You take Byetta by giving yourself an injection under the skin subcutaneous of your upper arm, thigh, or abdomen.
Your doctor will show you how to do this. You should give yourself an injection of Byetta twice a day, in the hour before each of your two main meals. Most people give themselves one injection in the hour before breakfast, and another in the hour before dinner. Your second injection would still be in the hour before your dinner, as long as these meals are at least six hours apart. Byetta has to be taken in the hour before a meal.
Just leave out that dose. Drinking too much alcohol can cause your blood sugar level to fall. Using alcohol while taking Byetta could raise your risk of hypoglycemia having your blood sugar level fall too low. If you drink alcohol, talk with your doctor about how much alcohol is safe to drink while you are using Byetta.
Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe. Below is a list of medications that can interact with Byetta. This list does not contain all drugs that may interact with Byetta. Before taking Byetta, talk with your doctor and pharmacist.
Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Byetta makes your stomach empty more slowly. Because of this, you should try to avoid taking medications by mouth for a few hours after giving yourself the Byetta injection. This could make them less effective. This gives them time to pass through your stomach and be absorbed through your small intestine. This is particularly important for antibiotics drugs used to treat bacterial infections and birth control pills. If you are supposed to take your other medications with a meal, you should take them with a meal when you are not having a Byetta injection.
You may use Byetta with other drugs for your diabetes. Your doctor may need to reduce the doses of your other drugs to avoid this. If you use Byetta with warfarin, this could increase your risk of bleeding. Your doctor may want to check how long it takes your blood to clot after you start treatment with Byetta and after any dose increases. Depending on the results, your doctor may reduce your warfarin dose.
Byetta can be used with metformin Glucophage, Fortamet, Glumetza, Riomet to treat type 2 diabetes. This combination is safe to use together. However, you should still check with your doctor or pharmacist before using any of these products while taking Byetta.
Studies in animals have shown some harmful effects on the fetus of a pregnant female given the drug. However, animal studies do not always predict what will happen in humans. Before you start using Byetta, let your doctor know if you are pregnant or think you could be pregnant.
If you are planning a pregnancy, talk with your doctor about the possible risks and benefits of using Byetta. If you would like to breastfeed while using Byetta, talk with your doctor about the possible risks and benefits.
You can also call the American Association of Poison Control Centers at or use their online tool. But if your symptoms are severe, call or go to the nearest emergency room right away. If you have type 2 diabetes , your body has trouble controlling the level of sugar glucose in your blood.
This is because the cells in your body have built up a resistance to the effects of insulin. Insulin is the main hormone responsible for lowering your blood sugar levels. Over time, your body may also produce less insulin. When you eat, your small intestine produces a hormone called GLP As the food starts to be absorbed into your blood, the level of glucose sugar in your blood starts to rise. GLP-1 stimulates your pancreas to release insulin into your bloodstream in response to the rise in blood sugar.
Insulin directs cells in your body to remove glucose from your blood, and this lowers your blood sugar level. GLP-1 also has some other actions that help control your blood sugar. It stops your pancreas from releasing a hormone called glucagon. Glucagon normally makes your liver produce glucose. If less glucagon is produced, it lowers your blood sugar level. In addition, GLP-1 also helps regulate your appetite. It slows down the speed that food moves through your stomach and into your small intestine.
This makes you feel fuller sooner. GLP-1 also acts in your brain to reduce your appetite. The active ingredient in Byetta is called exenatide. This is a type of drug called a glucagon-like peptide-1 GLP-1 receptor agonist.
Byetta acts in a similar way to the hormone called GLP-1 that your intestine releases when you eat. This means it produces the same four effects as GLP These actions allow Byetta to help lower your blood sugar level after eating a meal and keep it lower between meals. Byetta starts to work as soon as you inject a dose.
It keeps building up an effect over the next couple of hours. Byetta has a similar effect to mealtime insulin fast-acting insulin because it makes your body produce more insulin in response to a meal.
However, it also has other effects that help control your blood sugar between meals, as well as immediately after meals. This depends on your individual situation. They may prescribe one of the many type 2 diabetes drugs that are now available, or they may prescribe insulin. Insulin can be used for both type 2 and type 1 diabetes. Byetta can be used along with a long-acting insulin such as insulin glargine. However, Byetta is not recommended for use with meal-time insulins.
Type 1 diabetes has to be treated with insulin injections.
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