Previous research showed that DMSO in combination with cimetidine was more effective than cimetidine alone. These trials used mg of DMSO taken four times per day. The authors of these trials believe the antioxidant activity of DMSO may have a protective effect.
Oral supplementation with DMSO should not be attempted without the supervision of a doctor. The use of DMSO , a colorless, oily liquid primarily used as an industrial solvent, for therapeutic applications is controversial.
However, some evidence indicates that dilutions, when applied directly to the skin, have anti-inflammatory properties and inhibit the transmission of pain messages by nerves, and in this way might ease the pain of minor injuries such as sprains and strains. However no controlled research exists to confirm these effects in sprains and strains. DMSO comes in different strengths and different degrees of purity. In addition, certain precautions must be taken when applying DMSO.
For those reasons, DMSO should be used only with the supervision of a doctor. DMSO is not indicated for healthy people. Those who do use this substance should consult a doctor familiar with its use. Some physicians do not recommend the use of DMSO due to concerns about safety and questions about efficacy. The potential for contamination exists in some DMSO products designed for industrial uses.
DMSO used topically is rapidly absorbed through intact skin. DMSO is derived from trees as a manufacturing by-product from the processing of paper. Metabolites breakdown products of DMSO, such as the sulfide and sulfone forms, are naturally present in the human body. However, the role of these in the body is not clear. DMSO is not an essential nutrient and it is not needed in the functions of a healthy body; therefore, deficiencies do not exist. DMSO frequently causes a garlic -like body odor and taste in the mouth.
Other reported side effects include stomach upset , sensitivity to light , visual disturbances, and headache. Skin irritation can develop at the site where DMSO is applied topically. Only highly purified, properly diluted DMSO should be used and the skin site and applying hand should be thoroughly cleaned before application, because the solvent properties of DMSO allow contaminants to be absorbed through the skin and transported into the bloodstream.
Improperly diluted DMSO can also burn the skin. Check with a healthcare professional for appropriate use. Learn more about TraceGains, the company. The information presented by TraceGains is for informational purposes only.
It is based on scientific studies human, animal, or in vitro , clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available.
Information expires December This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use.
Learn how we develop our content. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. Uses DMSO dimethyl sulfoxide is a colorless, slightly oily liquid that is primarily used as an industrial solvent.
What Are Star Ratings? This supplement has been used in connection with the following health conditions: Used for Why 3 Stars. Some veterinarians add it in low concentrations to flushes used to rinse out draining abscesses or other infected wounds. Baker uses DMSO when he flushes out guttural pouches: "It's not irritating when it's diluted enough, and it does help liquefy a lot of the heavy, purulent material that is often found in the guttural pouch.
Because DMSO carries molecules through the skin and into the body, it's important to make sure the skin is clean and free of any other chemicals that could be inadvertently carried into the bloodstream. Fly sprays, for example, are safe when used as directed on the skin, but they contain chemicals that could become toxic if they are absorbed into the body.
The insecticide or parasiticide would have been fine used alone, but when combined with DMSO it will potentiate or increase the effects of that drug and make it toxic to the animal.
Many liniments also contain ingredients that are toxic if taken internally. Iodine is not as toxic to the horse, but could also cause a problem. Certain other drugs like alcohol, insulin, corticosteroids and atropine may be made more powerful if used concurrently with DMSO. This ability of DMSO to ease absorption of other topical products is also an issue if a horse is to be drug-tested for competition. But if you combine it with DMSO the drug level will be too high within the body and will cause a positive test.
Because DMSO is a powerful diuretic as well as a vasodilator, it can be harmful when given to dehydrated horses and those in shock. If the animal is in shock, this would make the condition worse. DMSO produces heat when applied with other solutions, such as water or saline, alcohol or acetone, which can have therapeutic benefits—but too high a concentration can actually burn the skin. Veterinarians often recommend mixing DMSO with Furacin ointment, which buffers it to reduce burning of the skin.
Some horses may be more sensitive to this effect than others. Intravenous administration of DMSO also carries the risk of side effects. Large intravenous doses may also destroy red blood cells and inhibit clotting.
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